Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate + a quinone | Corynebacterium glutamicum | - |
acetate + CO2 + a quinol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium glutamicum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate + a quinone | - |
Corynebacterium glutamicum | acetate + CO2 + a quinol | - |
? | |
pyruvate + oxidized 2,6-dichloroindophenol | activity assayed photometrically by monitoring the reduction of 2,6-dichloroindophenol, pH 6.0, 40°C | Corynebacterium glutamicum | acetate + CO2 + reduced 2,6-dichloroindophenol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
pqo | - |
Corynebacterium glutamicum |
pyruvate:quinone oxidoreductase | - |
Corynebacterium glutamicum |
General Information | Comment | Organism |
---|---|---|
physiological function | inactivation of the chromosomal pqo gene leads to the absence of pyruvate:quinone oxidoreductase activity. Growth and amino acid production are not affected under either condition tested. Introduction of plasmid-bound pqo into a pyruvate dehydrogenase complex-negative strain partially relieves the growth phenotype of this mutant, indicating that high pyruvate:quinone oxidoreductase activity can compensate for the function of the pyruvate dehydrogenase complex | Corynebacterium glutamicum |