Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | effects of several plant hormones and auxin derivatives | Arabidopsis thaliana |
Cloned (Comment) | Organism |
---|---|
gene iar4, wild-type sequencing and chromosomal mapping to a 45 kb region 35 cM from the top of chromosome 1 between the markers F3I6.8 and F3I6.17, DNA sequence determination of iar4-1 mutant | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of the iar4-1 mutant, defective in gene iar4 encoding the enzyme E1, by ethylmethane sulfonate, the mutant is less sensitive to a synthetic auxin and low concentrations of an ethylene precursor, but responds to free indole-3-acetic acid and other hormones in a way similar to the wild-type, the Krebs cycle and glycolysis are unaffected | Arabidopsis thaliana |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | effects of several plant hormones and auxin derivatives | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Arabidopsis thaliana | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Arabidopsis thaliana | conjugates of indole-3-acetic acid with amino acids act as hormones and e.g. inhibit root elongation, the sensitivity of the mutant iar4-1 plant against these conjugates and plant hormones is reduced compared to the wild-type, overview | ? | - |
? | |
pyruvate + CoA + NAD+ | Arabidopsis thaliana | - |
acetyl-CoA + CO2 + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
E1alpha component of the pyruvate dehydrogenase multienzyme complex PDH | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | conjugates of indole-3-acetic acid with amino acids act as hormones and e.g. inhibit root elongation, the sensitivity of the mutant iar4-1 plant against these conjugates and plant hormones is reduced compared to the wild-type, overview | Arabidopsis thaliana | ? | - |
? | |
pyruvate + CoA + NAD+ | - |
Arabidopsis thaliana | acetyl-CoA + CO2 + NADH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
E1alpha | component of the pyruvate dehydrogenase multienzyme complex PDH | Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Arabidopsis thaliana | |
thiamine diphosphate | - |
Arabidopsis thaliana |