Inhibitors | Comment | Organism | Structure |
---|---|---|---|
selenium | enzyme activity towards substrates (S)-4-(4-cyanoanilino)-5,6-dihydro-7-hydroxy-7H-cyclopenta[d]-pyrimidine and vanillin is increased by selenium deficiency to 250% of initial rate, and this corresponds to an increase of Aox1 protein level, but not to a decrease in mRNA level | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.014 | - |
Vanillin | pH 7.4, 37°C | Rattus norvegicus | |
0.0158 | - |
Vanillin | pH 7.4, 37°C, enzyme isolated from animals fed with a selenium-deficient diet | Rattus norvegicus | |
0.0341 | - |
(S)-4-(4-cyanoanilino)-5,6-dihydro-7-hydroxy-7H-cyclopenta[d]-pyrimidine | pH 7.4, 37°C | Rattus norvegicus | |
0.0407 | - |
(S)-4-(4-cyanoanilino)-5,6-dihydro-7-hydroxy-7H-cyclopenta[d]-pyrimidine | pH 7.4, 37°C, enzyme isolated from animals fed with a selenium-deficient diet | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-4-(4-cyanoanilino)-5,6-dihydro-7-hydroxy-7H-cyclopenta[d]-pyrimidine + H2O + O2 | i.e. S-8359 | Rattus norvegicus | ? + H2O2 | - |
? | |
vanillin + H2O + O2 | - |
Rattus norvegicus | vanillic acid + H2O2 | - |
? |