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Literature summary for 1.2.1.9 extracted from

  • Iglesias, A.A.; Vicario, L.R.; Gomez-Casati, D.F.; Sesma, J.I.; Gomez-Casati, M.E.; Bustos, D.M.; Podesta, F.E.
    On the interaction of substrate analogues with non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from celery leaves (2002), Plant Sci., 162, 689-696.
No PubMed abstract available
Search for more literature for 1.2.1.9

Inhibitors

Inhibitors Comment Organism Structure
3-aminopyridine competitive Apium graveolens
beta-Glycerophosphate competitive Apium graveolens
D-3-phosphoglycerate competitive Apium graveolens
DL-alpha-glycerophosphate competitive Apium graveolens
DL-glyceraldehyde competitive Apium graveolens
L-alpha-glycerophosphate competitive Apium graveolens
L-Glyceraldehyde 3-phosphate competitive below 0.04 mM, non-competitive above 0.075 mM Apium graveolens
Thionicotinamide competitive Apium graveolens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.007
-
 NADP+
-
 Apium graveolens
0.016
-
 3-acetylpyridine-adenine dinucleotide phosphate
-
 Apium graveolens
0.033
-
 nicotinamide-hypoxanthine dinucleotide phosphate
-
 Apium graveolens
0.04
-
 1,N6-ethenoadenine-nicotinamide dinucleotide phosphate
-
 Apium graveolens
0.08
-
 beta-nicotinamide adenine dinucleotide 2',3'-cyclic monophosphate
-
 Apium graveolens

Organism

Organism UniProt Comment Textmining
Apium graveolens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Apium graveolens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glyceraldehyde-3-phosphate + 1,N6-ethenoadenine-nicotinamide dinucleotide phosphate
-
 Apium graveolens D-3-phosphoglycerate + ?
-
 ?
D-glyceraldehyde-3-phosphate + 3-acetylpyridine-adenine dinucleotide phosphate
-
 Apium graveolens D-3-phosphoglycerate + ?
-
 ?
D-glyceraldehyde-3-phosphate + beta-nicotinamide adenine dinucleotide 2',3'-cyclic monophosphate
-
 Apium graveolens D-3-phosphoglycerate + ?
-
 ?
D-glyceraldehyde-3-phosphate + NADP+
-
 Apium graveolens D-3-phosphoglycerate + NADPH
-
 ?
D-glyceraldehyde-3-phosphate + nicotinamide-hypoxanthine dinucleotide phosphate
-
 Apium graveolens D-3-phosphoglycerate + ?
-
 ?

Synonyms

Synonyms Comment Organism
GAPN
-
 Apium graveolens
non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase
-
 Apium graveolens

Cofactor

Cofactor Comment Organism Structure
1,N6-ethenoadenine-nicotinamide dinucleotide phosphate
-
 Apium graveolens
3-acetylpyridine-adenine dinucleotide phosphate
-
 Apium graveolens
beta-nicotinamide adenine dinucleotide 2',3'-cyclic monophosphate
-
 Apium graveolens
NADP+
-
 Apium graveolens
nicotinamide-hypoxanthine dinucleotide phosphate
-
 Apium graveolens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00034
-
 Thionicotinamide
-
 Apium graveolens
0.00045
-
 3-aminopyridine
-
 Apium graveolens
0.0055
-
 L-Glyceraldehyde 3-phosphate competitive below 0.04 mM Apium graveolens
0.037
-
 L-Glyceraldehyde 3-phosphate noncompetitive above 0.075 mM Apium graveolens
0.339
-
 beta-Glycerophosphate
-
 Apium graveolens
0.45
-
 DL-alpha-glycerophosphate
-
 Apium graveolens
0.525
-
 D-3-phosphoglycerate
-
 Apium graveolens
0.94
-
 L-alpha-glycerophosphate
-
 Apium graveolens
1.05
-
 DL-glyceraldehyde
-
 Apium graveolens