Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NH4+ | slight activation up to about 0.3 M | Sus scrofa | |
Pro | 0.1 M, 35% activation, at high substrate concentrations | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glycine betaine | - |
Sus scrofa | |
K+ | 1.0 mM, 35% inhibition | Sus scrofa | |
Mg2+ | 0.4 M, complete inhibition | Sus scrofa | |
NaCl | 40% inhibition above 0.3 M | Sus scrofa | |
NH4+ | above 0.4 M, more than 60% inhibition | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | - |
NAD+ | - |
Sus scrofa | |
0.127 | - |
Betaine aldehyde | - |
Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | 0.2 M, slight activation | Sus scrofa | |
Na+ | slight activation up to about 0.3 M | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
x * 52000, SDS-PAGE | Sus scrofa |
688000 | - |
non-denaturing PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Sus scrofa |
Storage Stability | Organism |
---|---|
-70°C, stable for several months | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetaldehyde + NAD+ + H2O | at 20% of the activity with betaine aldehyde | Sus scrofa | acetate + NADH + H+ | - |
? | |
betaine aldehyde + NAD+ + H2O | - |
Sus scrofa | betaine + NADH | - |
ir | |
butyraldehyde + NAD+ + H2O | at 40% of the activity with betaine aldehyde | Sus scrofa | butyrate + NADH | - |
? | |
glyceraldehyde + NAD+ + H2O | at 30% of the activity with betaine aldehyde | Sus scrofa | glycerate + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 52000, SDS-PAGE | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.5 | - |
- |
Sus scrofa |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
5.5 | 9.5 | stable | Sus scrofa |