Literature summary for 1.2.1.8 extracted from

Hibino, T.; Meng, Y.L.; Kawamitsu, Y.; Uehara, N.; Matsuda, N.; Tanaka, Y.; Ishikawa, H.; Baba, S.; Takabe, T.; Wada, K.; Ishii, T.
Molecular cloning and functional characterization of two kinds of betaine-aldehyde dehydrogenase in betaine-accumulating mangrove Avicennia marina (Forsk.) Vierh (2001), Plant Mol. Biol., 45, 353-363.

Search for more literature for 1.2.1.8

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Avicennia marina

Inhibitors

Inhibitors	Comment	Organism	Structure
Ca2+	500 mM CaCl2, about 50% loss of activity	Avicennia marina
Ca2+	500 mM CaCl2, about 50% loss of activity	Bruguiera gymnorhiza
Ca2+	10 mM CaCl2, 90% inhibition	Escherichia coli
Ca2+	500 mM CaCl2, about 50% loss of activity	Rhizophora stylosa

Organism

Organism	UniProt	Comment	Textmining
Avicennia marina	-	-	-
Bruguiera gymnorhiza	-	-	-
Escherichia coli	-	-	-
Rhizophora stylosa	-	-	-
Spinacia oleracea	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant enzyme	Avicennia marina

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Spinacia oleracea	-
leaf	-	Avicennia marina	-
leaf	-	Bruguiera gymnorhiza	-
leaf	-	Rhizophora stylosa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
betaine aldehyde + NAD+ + H2O	-	Escherichia coli	betaine + NADH	-	?
betaine aldehyde + NAD+ + H2O	-	Spinacia oleracea	betaine + NADH	-	?
betaine aldehyde + NAD+ + H2O	-	Avicennia marina	betaine + NADH	-	?
betaine aldehyde + NAD+ + H2O	-	Bruguiera gymnorhiza	betaine + NADH	-	?
betaine aldehyde + NAD+ + H2O	-	Rhizophora stylosa	betaine + NADH	-	?

Temperature Stability [°C]

Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
45	-	120 min, about 80% decrease of activity	Spinacia oleracea
50	-	120 min, about 75% loss of activity	Avicennia marina
50	-	120 min, about 75% loss of activity	Bruguiera gymnorhiza
50	-	120 min, about 75% loss of activity	Rhizophora stylosa
50	-	120 min, complete inactivation	Spinacia oleracea

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Escherichia coli
NAD+	-	Spinacia oleracea

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Release 2023.1 (January 2023)