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Literature summary for 1.2.1.63 extracted from

  • Donoghue, N.A.; Trudgill, P.W.
    The metabolism of cyclohexanol by Acinetobacter NCIB 9871 (1975), Eur. J. Biochem., 60, 1-7.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-oxohexanoate + NADP+ + H2O Nocardia globerula
-
adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O Acinetobacter sp.
-
adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O Acinetobacter sp. NCIB 9871
-
adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O Nocardia globerula CL1
-
adipate + NADPH
-
?

Organism

Organism UniProt Comment Textmining
Acinetobacter sp.
-
-
-
Acinetobacter sp. NCIB 9871
-
-
-
Nocardia globerula
-
-
-
Nocardia globerula CL1
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture inducible enzyme synthesis by growth in cyclohexanol Nocardia globerula
-
cell culture inducible enzyme synthesis by growth in cyclohexanol Acinetobacter sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-oxohexanoate + NADP+ + H2O
-
Nocardia globerula adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O
-
Acinetobacter sp. adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O
-
Acinetobacter sp. NCIB 9871 adipate + NADPH
-
?
6-oxohexanoate + NADP+ + H2O
-
Nocardia globerula CL1 adipate + NADPH
-
?

Cofactor

Cofactor Comment Organism Structure
NADP+ can not replaced by NAD+ Acinetobacter sp.