Activating Compound | Comment | Organism | Structure |
---|---|---|---|
L-2-Aminopropan-1-ol | activation of aldehyde oxidation | Rattus norvegicus | |
L-serine methyl ester | activation of aldehyde oxidation | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
methylglyoxal + NADP+ + H2O | Rattus norvegicus | - |
pyruvate + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using ammonium sulfate fractionation and chromatography on DEAE-Sephadex A-50 column, Blue-dextran affinity column and CM-Sephadex C-50 column | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
7.25 | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C, 50% glycerol | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methylglyoxal + NADP+ + H2O | - |
Rattus norvegicus | pyruvate + NADPH + H+ | - |
? | |
additional information | L-serine methyl ester or L-2-aminopropan-1-ol are necessary to activate the enzyme | Rattus norvegicus | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Rattus norvegicus |