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Literature summary for 1.2.1.46 extracted from

  • Achmann, S.; Hermann, M.; Hilbrig, F.; Jerome, V.; Haemmerle, M.; Freitag, R.; Moos, R.
    Direct detection of formaldehyde in air by a novel NAD+- and glutathione-independent formaldehyde dehydrogenase-based biosensor (2008), Talanta, 75, 786-791.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
methanol stabilizes Hyphomicrobium zavarzinii

Application

Application Comment Organism
industry amperometric enzyme-based sensor-system for the direct detection of formaldehyde in air, based on a native bacterial NAD+- and glutathione-independent formaldehyde dehydrogenase as biorecognition element. With the elimination of NAD+ it is much more promising to obtain a sensor device with higher long-term stability Hyphomicrobium zavarzinii

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ plays an important role in the active centre of DL-FDH and for the sensing purpose Hyphomicrobium zavarzinii

Organism

Organism UniProt Comment Textmining
Hyphomicrobium zavarzinii
-
-
-
Hyphomicrobium zavarzinii ZV 580
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partially purified Hyphomicrobium zavarzinii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
formaldehyde + H2O + NAD+
-
Hyphomicrobium zavarzinii formate + NADH + H+
-
?
formaldehyde + H2O + NAD+
-
Hyphomicrobium zavarzinii ZV 580 formate + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
DL-FDH
-
Hyphomicrobium zavarzinii
dye-linked formaldehyde dehydrogenase
-
Hyphomicrobium zavarzinii
NAD+- and glutathione-independent formaldehyde dehydrogenase
-
Hyphomicrobium zavarzinii

Cofactor

Cofactor Comment Organism Structure
additional information pyrroloquinoline quinone may be the bound cofactor Hyphomicrobium zavarzinii