Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phosphate | 100 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.19 | - |
NADP+ | - |
Rattus norvegicus | |
1.8 | - |
L-glutamate 5-semialdehyde | - |
Rattus norvegicus | |
11.3 | - |
phosphate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelium | of the intestine | Rattus norvegicus | - |
intestine | epithelium | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate 5-semialdehyde + phosphate + NADP+ | L-glutamate 5-semialdehyde spontaneously cyclizes to delta-1-pyrroline-5-carboxylic acid | Rattus norvegicus | L-5-glutamyl phosphate + NADPH | - |
? | |
L-glutamate 5-semialdehyde + phosphate + NADP+ | L-glutamate 5-semialdehyde spontaneously cyclizes to pyrroline 5-carboxylate. The product gamma-glutamyl phosphate decomposes to pyrrolidone 5-carboxylate. | Rattus norvegicus | gamma-glutamyl phosphate + NADPH + H+ | - |
r |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |