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Literature summary for 1.2.1.4 extracted from

  • Lassen, N.; Bateman, J.B.; Estey, T.; Kuszak, J.R.; Nees, D.W.; Piatigorsky, J.; Duester, G.; Day, B.J.; Huang, J.; Hines, L.M.; Vasiliou, V.
    Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice (2007), J. Biol. Chem., 282, 25668-25676.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.4

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
51000
-
 SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cornea
-
 Mus musculus
-
additional information undetectable in the lens Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.853
-
 wild type enzyme from cornea, using propionaldehyde and NAD+ as substrates Mus musculus
3.43
-
 wild type enzyme from cornea, using NADP+ and benzaldehyde as substrates Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxy-2-nonenal + NADP+
-
 Mus musculus (2E)-4-hydroxynon-2-enoate + NADPH + H+
-
 ?
benzaldehyde + NADP+
-
 Mus musculus benzoate + NADPH + H+
-
 ?
malondialdehyde + NADP+ poor substrate Mus musculus ?
-
 ?
propionaldehyde + NADP+ poor substrate Mus musculus propionate + NADPH + H+
-
 ?

Synonyms

Synonyms Comment Organism
aldehyde dehydrogenase 3A1
-
 Mus musculus
ALDH3A1
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Mus musculus