Literature summary for 1.2.1.36 extracted from

Goswami, S.; Angkasekwinai, P.; Shan, M.; Greenlee, K.J.; Barranco, W.T.; Polikepahad, S.; Seryshev, A.; Song, L.Z.; Redding, D.; Singh, B.; Sur, S.; Woodruff, P.; Dong, C.; Corry, D.B.; Kheradmand, F.
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma (2009), Nat. Immunol., 10, 496-503.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	upregulated in response to allergic stimulation in the airway epithelium	Mus musculus

Application

Application	Comment	Organism
medicine	RALDH1 is a negative regulator of allergic inflammation	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
citral	-	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P24549	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
alveolar macrophage	-	Mus musculus	-
epithelial cell	airway epithelial cell	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
all-trans retinaldehyde + NAD+ + H2O	-	Mus musculus	all-trans retinoic acid + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
RalDH1	-	Mus musculus
retinal dehydrogenase 1	-	Mus musculus

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Release 2023.1 (January 2023)