Cloned (Comment) | Organism |
---|---|
into the vector pT7.7 for expression in Escherichia coli BL21DE3 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Chloral hydrate | - |
Homo sapiens | |
daidzin | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00033 | - |
acetaldehyde | - |
Homo sapiens | |
0.2 | - |
acetaldehyde | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
by p-hydroxyacetophenone affinity chromatography | Homo sapiens |
by p-hydroxyacetophenone affinity chromatography and gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00018 | - |
conversion of glycerol trinitrate to 1,3-glycerol dinitrate | Homo sapiens |
0.00066 | - |
conversion of glycerol trinitrate to 1,3-glycerol dinitrate | Homo sapiens |
0.003 | - |
conversion of glycerol trinitrate to 1,2-glycerol dinitrate | Homo sapiens |
0.009 | - |
conversion of glycerol trinitrate to 1,2-glycerol dinitrate | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetaldehyde + NAD+ + H2O | activity assay | Homo sapiens | acetate + NADH + H+ | - |
? | |
glyceryl trinitrate + NADH + H+ | - |
Homo sapiens | 1,2-glyceryl dinitrate + nitrite + NAD+ | - |
? | |
glyceryl trinitrate + NADH + H+ | - |
Homo sapiens | 1,3-glyceryl dinitrate + nitrite + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aldehyde dehydrogenase 1 | - |
Homo sapiens |
aldehyde dehydrogenase 2 | - |
Homo sapiens |
ALDH1 | - |
Homo sapiens |
ALDH2 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
activity assay | Homo sapiens |
37 | - |
incubation of ALDH with 14C-labeled nitroglycerin | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
incubation of ALDH with 14C-labeled nitroglycerin | Homo sapiens |
9 | - |
activity assay | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |