Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetaldehyde + NAD+ + H2O | Rattus norvegicus | rats with an mutated allele for aldehyde dehydrogenase (ALDH2-2) show a low alcohol consumption phenotype. Homozygous ALDH2-2 rats derived from high-drinker F0 females showed a remarkly higher ethanol consumption than homozygous animals derived from low-drinker females. Mitochondria of F2 rats derived from high alcohol-consuming females were more active in oxidizing substrates that generate NADH for complex I | acetate + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P11884 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetaldehyde + NAD+ + H2O | rats with an mutated allele for aldehyde dehydrogenase (ALDH2-2) show a low alcohol consumption phenotype. Homozygous ALDH2-2 rats derived from high-drinker F0 females showed a remarkly higher ethanol consumption than homozygous animals derived from low-drinker females. Mitochondria of F2 rats derived from high alcohol-consuming females were more active in oxidizing substrates that generate NADH for complex I | Rattus norvegicus | acetate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aldehyde dehydrogenase | - |
Rattus norvegicus |
ALDH2 | - |
Rattus norvegicus |