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Literature summary for 1.2.1.3 extracted from
- Human liver aldehyde dehydrogenase. Kinetics of aldehyde oxidation (1975), J. Biol. Chem., 250, 7899-7904.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| adenine | - |
Homo sapiens |  |
| adenosine | - |
Homo sapiens | |
| Chloral hydrate | - |
Homo sapiens | |
| glyceraldehyde | substrate inhibition | Homo sapiens | |
| N'-methylnicotinamide | - |
Homo sapiens | |
| NADH | product inhibition | Homo sapiens | |
| thio-NAD+ | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| an aldehyde + NAD+ + H2O = a carboxylate + NADH + H+ | sequential addition of both substrates prior to release of products | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glyceraldehyde + NAD+ + H2O | - |
Homo sapiens | glycerate + NADH | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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