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Literature summary for 1.2.1.24 extracted from
- Succinic semialdehyde dehydrogenase. Reactivity of lysyl residues (1979), J. Biol. Chem., 254, 1794-1798.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-hydroxybenzaldehyde | - |
Sus scrofa |  |
| m-hydroxybenzaldehyde | - |
Sus scrofa | |
| o-phthalaldehyde | binding of 10 mol per mol of enzyme results in irreversible loss of activity | Sus scrofa | |
| pyridoxal 5'-phosphate | NAD+ protects | Sus scrofa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 5.3 | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate semialdehyde + NAD+ + H2O | - |
Sus scrofa | succinate + NADH | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 9.5 | - |
Sus scrofa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Sus scrofa | |
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Release 2023.1 (January 2023)
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