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Literature summary for 1.2.1.12 extracted from

  • Munoz-Bertomeu, J.; Cascales-Minana, B.; Mulet, J.M.; Baroja-Fernandez, E.; Pozueta-Romero, J.; Kuhn, J.M.; Segura, J.; Ros, R.
    Plastidial glyceraldehyde-3-phosphate dehydrogenase deficiency leads to altered root development and affects the sugar and amino acid balance in Arabidopsis (2009), Plant Physiol., 151, 541-558.
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
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 Arabidopsis thaliana 9507
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plastid
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 Arabidopsis thaliana 9536
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q5E924 isoform GAPCp2
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Arabidopsis thaliana Q9SAJ6 isoform GAPCp1
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General Information

General Information Comment Organism
physiological function double mutants lacking both plastidial isoforms gapcp1 and gapcp2 display a drastic phenotype of arrested root development, dwarfism, and sterility. In spite of their low gene expression level, GAPCp down-regulation leads to altered gene expression and to drastic changes in the sugar and amino acid balance of the plant. GAPCps are important for the synthesis of serine in roots. Serine supplementation to the growth medium rescues root developmental arrest and restores normal levels of carbohydrates and sugar biosynthetic activities in gapcp double mutants Arabidopsis thaliana