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Literature summary for 1.17.4.4 extracted from

  • Spreafico, M.; Loadigiani, C.; van Leeuwen, Y.; Pizzotti, D.; Rota, L.L.; Rosendaal, F.R.; Mannucci, P.M.; Peyvandi, F.
    Effects of CYP2C9 and VKORC1 on INR variations and dose rewuirements during initial phase of anticoagulant therapy (2008), Pharmacogenomics, 9, 1237-1250.
    View publication on PubMed

Application

Application Comment Organism
medicine the determination of VKORC1-3 and VKORC1-4 haplotypes may be an important addition to CYP2C9 and VKORC1-2 genotyping to identify patients at risk of being outside the target range during initial anticoagulation with acenocoumarol Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
warfarin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
vitamin K epoxide reductase complex subunit 1
-
Homo sapiens
VKORC1
-
Homo sapiens