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Literature summary for 1.17.4.2 extracted from

  • Saiko, P.; Ozsvar-Kozma, M.; Bernhaus, A.; Jaschke, M.; Graser, G.; Lackner, A.; Grusch, M.; Horvath, Z.; Madlener, S.; Krupitza, G.; Handler, N.; Erker, T.; Jaeger, W.; Fritzer-Szekeres, M.; Szekeres, T.
    N-hydroxy-N-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine (2007), Int. J. Oncol., 31, 1261-1266.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine a resveratrol analogue, inhibits the enzyme in HL-60 cells showing synergistic effects with arabinofuranosylcytosine in antitumor activity, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
HL-60 cell
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Homo sapiens
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promyelocytic leukemia cell
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Homo sapiens
-