Literature summary for 1.17.4.1 extracted from

Heidel, J.D.; Liu, J.Y.; Yen, Y.; Zhou, B.; Heale, B.S.; Rossi, J.J.; Bartlett, D.W.; Davis, M.E.
Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo (2007), Clin. Cancer Res., 13, 2207-2215.

Search for more literature for 1.17.4.1

Application

Application	Comment	Organism
medicine	ribonucleotide reductase is a therapeutic target for DNA replication-dependent diseases such as cancer in humans	Mus musculus

Cloned(Commentary)

Cloned (Comment)	Organism
expression analysis of mouse RRM2 protein in Hep-G2 cells	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	transfection of RRM2 protein-expressing Hep-G2 cells with constructed potent siRNA, NM_009104, inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo, overview	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	female BALB/c mice and A/J mice	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Neuro2A-Luc cell	from A/J mice	Mus musculus	-

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Release 2023.1 (January 2023)