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Literature summary for 1.17.4.1 extracted from

  • Lang, P.; Gerez, C.; Tritsch, D.; Fontecave, M.; Biellmann, J.F.; Burger, A.
    Synthesis of 8-vinyladenosine 5'-di- and 5'-triphosphate: evaluation of the diphosphate compound on ribonucleotide reductase (2003), Tetrahedron, 59, 7315-7322.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
additional information 8-vinyl-ADP is efficiently reduced. The anti-tumoral and anti-viral activity of 8-vinyladenosine can unlikely result from inhibition of ribonucleotide diphosphate reductase Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
8-vinyl-ADP + reduced thioredoxin
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Escherichia coli 8-vinyl-2'-deoxy-ADP + thioredoxin disulfide + H2O
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