Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | enhance oxidation of dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus | |
glutathione | enhances oxidation of dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus | |
N-acetyl-L-Cys | enhance oxidation of dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
allopurinol | competitive inhibition of oxidation of dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus | |
desferrioxamine | significant decrease in CN- formation from dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus | |
dimethylthiourea | significant decrease in rate of oxidation of dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus | |
folic acid | uncompetitive inhibition of oxidation of dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus | |
mannitol | significant decrease in rate of oxidation of dibromoacetonitrile by the hypoxanthine/xanthine oxidase/Fe system | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
97 | - |
dibromoacetonitrile | - |
Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dibromoacetonitrile + H2O + O2 | - |
Bos taurus | ? | - |
r | |
additional information | hydroxyl free radicals generated by the hypoxanthine/xanthine oxidase/Fe system are implicated in oxidation of dibromoacetonitrile to CN- | Bos taurus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
conversion of dibromoacetonitrile to CN- | Bos taurus |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | 45 | 30°C: about 60% of maximal activity, 45°C: about 75% of maximal activity, conversion of dibromoacetonitrile to CN- | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
conversion of dibromoacetonitrile to CN- | Bos taurus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 9.5 | pH 6.5: about 40% of maximal activity, pH 9.5: about 65% of maximal activity, conversion of dibromoacetonitrile to CN- | Bos taurus |