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Literature summary for 1.17.3.2 extracted from
- Purification and characterization of xanthine oxidase from livers of vitamin E deficient rabbits (1975), Biochim. Biophys. Acta, 377, 34-41.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Oryctolagus cuniculus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Iron | iron-molybdenum protein | Oryctolagus cuniculus |  |
| Molybdenum | an iron-molybdenum protein | Oryctolagus cuniculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 52000 | - |
x * 52000 + x * 99000, SDS-PAGE | Oryctolagus cuniculus |
| 99000 | - |
x * 52000 + x * 99000, SDS-PAGE | Oryctolagus cuniculus |
| 280000 | - |
gel filtration | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| additional information | - |
Oryctolagus cuniculus |
| proteolytic modification | - |
Oryctolagus cuniculus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.278 | - |
- |
Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hypoxanthine + 2 H2O + 2 O2 | - |
Oryctolagus cuniculus | urate + 2 H2O2 | - |
? | |
| xanthine + H2O + O2 | electron acceptor O2 | Oryctolagus cuniculus | uric acid + H2O2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| oligomer | x * 52000 + x * 99000, SDS-PAGE | Oryctolagus cuniculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.1 | - |
- |
Oryctolagus cuniculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7.7 | 9.1 | at pH 7.7 and 9.1: about 30% of activity maximum | Oryctolagus cuniculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | flavoprotein | Oryctolagus cuniculus | |
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Release 2023.1 (January 2023)
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