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Literature summary for 1.17.1.4 extracted from

  • Haidari, F.; Ali Keshavarz, S.; Reza Rashidi, M.; Mohammad Shahi, M.
    Orange juice and hesperetin supplementation to hyperuricemic rats alter oxidative stress markers and xanthine oxidoreductase activity (2009), J. Clin. Biochem. Nutr., 45, 285-291.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.17.1.4

Inhibitors

Inhibitors Comment Organism Structure
allopurinol shows strong enzyme inhibition and hypouricemic effect Rattus norvegicus
hesperetin i.e. 3',5,7-trihydroxy-4'-methoxyflavanone, major flavanone component of orange juice, inhibits hepatic XDH activity and decreases serum uric acid levels, exhibits antioxidative and antihyperuricemic properties Rattus norvegicus
additional information orange juice inhibits hepatic XDH activity and decreases serum uric acid levels and exhibits antioxidative and antihyperuricemic properties Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mo XOR is a molybdenum-containing enzyme Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus enzyme inhibition by orange juice and hesperetin participates in preventing oxidative stress by enhancing total antioxidant capacity and decreasing lipid peroxidation, overview ?
-
 ?
xanthine + NAD+ + H2O Rattus norvegicus
-
 urate + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme inhibition by orange juice and hesperetin participates in preventing oxidative stress by enhancing total antioxidant capacity and decreasing lipid peroxidation, overview Rattus norvegicus ?
-
 ?
xanthine + NAD+ + H2O
-
 Rattus norvegicus urate + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
XDH
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
molybdenum cofactor molybdenum-containing enzyme Rattus norvegicus
NAD+
-
 Rattus norvegicus