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Literature summary for 1.15.1.1 extracted from
- High-level expression of human extracellular superoxide dismutase in Escherichia coli and insect cells (2002), Protein Expr. Purif., 24, 13-17.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| EC-SOD, overexpression in Escherichia coli as His-tagged protein and in Tn-5B1-4 cells of Trichoplusia ni via baculovirus infection | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | EC-SOD with Cu,Zn-SOD activity | Homo sapiens | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | extracellular EC-SOD with Cu,Zn-SOD activity | Homo sapiens |  |
| Zn2+ | extracellular EC-SOD with Cu,Zn-SOD activity | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 28000 | - |
4 * 28000, recombinant EC-SOD, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
EC-SOD with Cu,Zn-SOD activity | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Homo sapiens |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| EC-SOD recombinant from Escherichia coli as His-tagged protein and partially from insect cells | Homo sapiens |
Renatured (Commentary)
| Renatured (Comment) | Organism |
|---|---|
| recombinant EC-SOD refolds from inclusion bodies in E. coli after denaturing | Homo sapiens |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
recombinant EC-SOD | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| O2- + H+ | - |
Homo sapiens | O2 + H2O2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 28000, recombinant EC-SOD, SDS-PAGE | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| EC-SOD | extracellular superoxide dismutase | Homo sapiens |
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Release 2023.1 (January 2023)
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