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Literature summary for 1.14.99.14 extracted from
- 11alpha-Hydroxylation of progesterone by cell free preparation of Aspergillus ochraceus TS (1981), J. Steroid Biochem., 14, 1063-1067.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cyanide | - |
Aspergillus ochraceus |  |
| sodium-meta-periodate | - |
Aspergillus ochraceus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Metyrapone | - |
Aspergillus ochraceus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| progesterone + NADPH + O2 | Aspergillus ochraceus | - |
11alpha-hydroxyprogesterone + NADP+ + H2O | - |
? | |
| progesterone + NADPH + O2 | Aspergillus ochraceus TS | - |
11alpha-hydroxyprogesterone + NADP+ + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus ochraceus | - |
- |
- |
| Aspergillus ochraceus TS | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| progesterone + NADPH + O2 | - |
Aspergillus ochraceus | 11alpha-hydroxyprogesterone + NADP+ + H2O | - |
? | |
| progesterone + NADPH + O2 | - |
Aspergillus ochraceus TS | 11alpha-hydroxyprogesterone + NADP+ + H2O | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome P450 | - |
Aspergillus ochraceus |
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