Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-Pregnene-3beta,20alpha-diol | - |
Ilyonectria destructans | |
dehydroepiandrosterone | - |
Ilyonectria destructans | |
pregnenolone | - |
Ilyonectria destructans | |
progesterone | - |
Ilyonectria destructans | |
testosterone | - |
Ilyonectria destructans | |
Testosterone acetate | - |
Ilyonectria destructans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
NADPH | - |
Ilyonectria destructans | |
0.04 | - |
androst-4-ene-3,17-dione | - |
Ilyonectria destructans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ilyonectria destructans | - |
the steroid monooxygenase also has androstenedione monooxygenase activity | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
androst-4-ene-3,17-dione + NADPH + O2 | - |
Ilyonectria destructans | 3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + NADP+ + H2O | testololactone | ? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.45 | - |
testololactone | formed | Ilyonectria destructans |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
- |
Ilyonectria destructans |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.7 | 7.8 | about 50% of activity maximum at pH 5.7 and 7.8 | Ilyonectria destructans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | absolute requirement | Ilyonectria destructans |