Literature summary for 1.14.20.1 extracted from

Chin, H.S.; Sim, T.S.
C-terminus modification of Streptomyces clavuligerus deacetoxycephalosporin C synthase improves catalysis with an expanded substrate specificity (2002), Biochem. Biophys. Res. Commun., 295, 55-61.

Search for more literature for 1.14.20.1

Protein Variants

Protein Variants	Comment	Organism
additional information	the truncation of the C-terminus at position 310 in the wild-type enzyme results in reduction of indiscriminate conversion of penicillin analog but this defect is compensated by the replacement of asparagine with leucine at position 304	Streptomyces clavuligerus
N304L	mutant enzyme with improved efficiency in penicillin conversion	Streptomyces clavuligerus
R306L	mutant enzyme with improved efficiency in penicillin conversion	Streptomyces clavuligerus
R307L	mutant enzyme with improved efficiency in penicillin conversion	Streptomyces clavuligerus

Organism

Organism	UniProt	Comment	Textmining
Streptomyces clavuligerus	P18548	-	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)