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Literature summary for 1.14.19.9 extracted from
- Purification and Partial Characterization of Tryptophan 7-Halogenase (PrnA) from Pseudomonas fluorescens (2000), Angew. Chem. Int. Ed. Engl., 39, 2300-2302.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan + FADH2 + Cl- + O2 + H+ | Pseudomonas fluorescens | the enzyme is involved in biosynthesis of pyrrolnitrin | 7-chloro-L-tryptophan + FAD + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas fluorescens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pseudomonas fluorescens |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
PrnA activities are determined after addition of flavin reductase (SsuE). Without reductase, fractions after elution from the molecular sieve column do not show any activity | Pseudomonas fluorescens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan + FADH2 + Cl- + O2 + H+ | the enzyme is involved in biosynthesis of pyrrolnitrin | Pseudomonas fluorescens | 7-chloro-L-tryptophan + FAD + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PrnA | - |
Pseudomonas fluorescens |
| Trp-7-Hal | - |
Pseudomonas fluorescens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FADH2 | the enzyme is specific for FADH2 | Pseudomonas fluorescens | |
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