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Literature summary for 1.14.19.30 extracted from

  • Saito, T.; Kato, A.; Ochiai, H.; Morita, N.
    Temperature adaptation in Dictyostelium: Role of DELTA5 fatty acid desaturase (2005), Microbiology, 151, 113-119.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum
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Dictyostelium discoideum AX2
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Synonyms

Synonyms Comment Organism
DELTA5 fatty acid desaturase
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Dictyostelium discoideum
FadA isoform Dictyostelium discoideum
FadB isoform Dictyostelium discoideum

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
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Dictyostelium discoideum

General Information

General Information Comment Organism
malfunction the lower dienoic acid content of the fadA mutant results in a tolerance of elevated temperatures during development, but not during the growth phase Dictyostelium discoideum
physiological function isoforms FadA and FadB are involved in temperature adaptation. Isoform FadA is mainly responsible for the production of dienoic fatty acids, whereas isoform FadB has a supplementary function Dictyostelium discoideum