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Literature summary for 1.14.19.3 extracted from

  • Guillou, H.; D'Andrea, S.; Rioux, V.; Jan, S.; Legrand, P.
    The surprising diversity of DELTA6-desaturase substrates (2004), Biochem. Soc. Trans., 32, 86-87.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitic acid + AH2 + O2 Rattus norvegicus key enzyme required for numerous vital functions involving distinct polyunsaturated fatty acids and polyunsaturated fatty acid-derived bioactive lipids. It seems that the biological importance of DELTA6-desaturase activity should also be considered for its newly identified role in the control of the biosynthesis of a monoenoic fatty acid (C16:1 n-10), particularly in tissues with low DELTA9-desaturase activity hexadec-6-enoic acid + A + H2O
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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enzyme expressed in COS cells
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitic acid + AH2 + O2
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Rattus norvegicus hexadec-6-enoic acid + A + H2O
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?
palmitic acid + AH2 + O2 key enzyme required for numerous vital functions involving distinct polyunsaturated fatty acids and polyunsaturated fatty acid-derived bioactive lipids. It seems that the biological importance of DELTA6-desaturase activity should also be considered for its newly identified role in the control of the biosynthesis of a monoenoic fatty acid (C16:1 n-10), particularly in tissues with low DELTA9-desaturase activity Rattus norvegicus hexadec-6-enoic acid + A + H2O
-
?

Synonyms

Synonyms Comment Organism
DELTA6 desaturase
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Rattus norvegicus
FADS2
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Rattus norvegicus