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Literature summary for 1.14.19.20 extracted from
- Amino acid substitutions in the Candida albicans sterol DELTA5,6-desaturase (Erg3p) confer azole resistance: Characterization of two novel mutants with impaired virulence (2012), J. Antimicrob. Chemother., 67, 2131-2138.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| L193R | the mutation impairs enzyme function | Candida albicans |
| additional information | mutant CAAL76 with a 13 bp deletion leading to a truncated enzyme (DELTA366-378) shows impaired enzyme function | Candida albicans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | J7FE12 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Erg3p | - |
Candida albicans |
| sterol DELTA5,6-desaturase | - |
Candida albicans |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome b5 | - |
Candida albicans |
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Release 2023.1 (January 2023)
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