Literature summary for 1.14.19.1 extracted from

Mainieri, D.; Summermatter, S.; Seydoux, J.; Montani, J.P.; Rusconi, S.; Russell, A.P.; Boss, O.; Buchala, A.J.; Dulloo, A.G.
A role for skeletal muscle stearoyl-CoA desaturase 1 in control of thermogenesis (2006), FASEB J., 20, 1751-1753.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	from skeletal muscle of Sprague-Dawley rats	Rattus norvegicus	-	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P07308	Sprague-Dawley rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adipose tissue	-	Rattus norvegicus	-
liver	-	Rattus norvegicus	-
skeletal muscle	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	Sprague-Dawley rats are food restricted at 50% of their spontaneous food intake for 2 weeks and than are refeeded, enzyme activity is significantly elevated at the end of 2 weeks of semistarvation, +72%, and remains higher on day 7 of refeeding, +44%	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
stearoyl-CoA + AH2 + O2	activity measured via the generation of tritium enriched water from the substrate 9,10-3H-steaoryl-CoA	Rattus norvegicus	oleoyl-CoA + A + H2O	-	?

Synonyms

Synonyms	Comment	Organism
SCD1	-	Rattus norvegicus

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Release 2023.1 (January 2023)