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Literature summary for 1.14.18.3 extracted from

  • Chan, S.I.; Yu, S.S.
    Controlled oxidation of hydrocarbons by the membrane-bound methane monooxygenase: the case for a tricopper cluster (2008), Acc. Chem. Res., 41, 969-979.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information pMMO with the full complement of copper ions does not require methanobactin for activity Methylococcus capsulatus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane integral membrane protein Methylococcus capsulatus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+ multicopper enzyme, contains 3 Cu2+ ions per trimer, contains 13.6 copper atoms per protein complex Methylococcus capsulatus
Zn2+ contains one Zn2+ ion in the transmembrane domain Methylococcus capsulatus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28328
-
1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus
29733
-
1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus
42785
-
1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus

Organism

Organism UniProt Comment Textmining
Methylococcus capsulatus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 1-butene + 2 reduced acceptor + 2 H+ + 2 O2
-
Methylococcus capsulatus 3-buten-2-ol + 1,2-epoxybutane + 2 acceptor + 2 H2O
-
?
2 butane + 2 reduced acceptor + 2 H+ + 2 O2
-
Methylococcus capsulatus 1-butanol + 2-butanol + 2 acceptor + 2 H2O
-
?
2 pentane + 2 reduced acceptor + 2 H+ + 2 O2
-
Methylococcus capsulatus 1-pentanol + 2-pentanol + 2 acceptor + 2 H2O
-
?
2 propane + 2 reduced acceptor + 2 H+ + 2 O2
-
Methylococcus capsulatus 1-propanol + 2-propanol + 2 acceptor + 2 H2O
-
?
3 cis-2-butene + reduced acceptor + H+ + O2
-
Methylococcus capsulatus meso-2,3-dimethyloxirane + acceptor + H2O
-
?
3,3,3-trifluoropropene + reduced acceptor + H+ + O2
-
Methylococcus capsulatus 3,3,3-trifluoro-1,2-epoxypropane + acceptor + H2O
-
?
methane + reduced acceptor + H* + O2
-
Methylococcus capsulatus methanol + acceptor + H2O
-
?
trans-2-butene + reduced acceptor + H+ + O2
-
Methylococcus capsulatus 2,3-dimethyloxirane + acceptor + H2O
-
?

Subunits

Subunits Comment Organism
heterotrimer 1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus

Synonyms

Synonyms Comment Organism
particulate methane monooxygenase
-
Methylococcus capsulatus
pMMO
-
Methylococcus capsulatus