Application | Comment | Organism |
---|---|---|
drug development | the suppression of tyrosinase activity by 2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate and the inhibition of tyrosinase production by terrein appear to be an optimal combination for skin whitening | Mus musculus |
drug development | the suppression of tyrosinase activity by 2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate and the inhibition of tyrosinase production by terrein appear to be an optimal combination for skin whitening | Agaricus bisporus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate | KI-063, a new tyrosinase inhibitor, strong concentration-dependent inhibitory effect on tyrosinase activity | Agaricus bisporus | |
2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate | KI-063 | Mus musculus | |
terrein | examine the effects of a combination of 2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate with terrein, an agent that down-regulates microphthalmia-associated transcription factor | Agaricus bisporus | |
terrein | examines the effects of a combination of 2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate with terrein, an agent that down-regulates microphthalmia-associated transcription factor. Cells co-treated with 2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate and terrein show much less pigmentation than cells treated with 2-butyl-5-hydroxyphenyl 3-(3,4-dihydroxyphenyl)propanoate or terrein alone | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Agaricus bisporus | - |
Mel-Ab cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-dopa + 1/2 O2 | - |
Mus musculus | L-dopaquinone + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Mus musculus |
tyrosinase | - |
Agaricus bisporus |