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Literature summary for 1.14.18.1 extracted from
- Inhibition of mushroom tyrosinase by tropolone (1985), Phytochemistry, 24, 905-908.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| anionic detergents | activation | Mushroom |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2,4,6-cycloheptatriene-1-one | copper chelator, trivial name tropolone, mixed inhibition, 90% reversible by dialysis, approx. 70% recovery by addition of CuSO4 | Mushroom |  |
| beta-(N-3-hydroxypyridone-4)-alpha-aminopropionic acid | 0.1 mM, 50% inhibition; copper chelator, trivial name L-mimosine | Mushroom | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.48 | - |
DL-dopa | - |
Mushroom | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mushroom | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| commercial preparation | - |
Mushroom | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DL-DOPA + O2 | - |
Mushroom | dopaquinone + H2O | - |
r | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.015 | - |
2,4,6-cycloheptatriene-1-one | - |
Mushroom | |
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