Literature summary for 1.14.17.3 extracted from

Bauman, A.T.; Jaron, S.; Yukl, E.T.; Burchfiel, J.R.; Blackburn, N.J.
pH Dependence of peptidylglycine monooxygenase. Mechanistic implications of Cu-methionine binding dynamics (2006), Biochemistry, 45, 11140-11150.

Search for more literature for 1.14.17.3

Cloned(Commentary)

Cloned (Comment)	Organism
expression in CHO DG44 cells	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.00091	-	dansyl-D-Tyr-Val-Gly	at pH 7.0	Rattus norvegicus
0.003	-	dansyl-D-Tyr-Val-Gly	at pH 6.0	Rattus norvegicus
0.0066	-	dansyl-D-Tyr-Val-Gly	at pH 5.0	Rattus norvegicus
0.0072	-	dansyl-D-Tyr-Val-Gly	at pH 5.5	Rattus norvegicus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Cu2+	requirred	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
two chromatography steps	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
cell culture	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dansyl-D-Tyr-Val-Gly + ascorbate + O2	-	Rattus norvegicus	dansyl-D-Tyr-Val-2-hydroxyglycine + dehydroascorbate + H2O	-	?

Synonyms

Synonyms	Comment	Organism
peptidylglycine alpha-hydroxylating monooxygenase	-	Rattus norvegicus
peptidylglycine monooxygenase	-	Rattus norvegicus
PHM	-	Rattus norvegicus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
5.8	-	-	Rattus norvegicus

pH Range

pH Minimum	pH Maximum	Comment	Organism
4	9	-	Rattus norvegicus

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Release 2023.1 (January 2023)