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Literature summary for 1.14.17.1 extracted from

  • Fortin, D.; Coulon, J.F.; Roberge, A.G.
    Comparative study of biochemical parameters and kinetic properties of dopamine-beta-hydroxylase activity from cat and rat adrenals (1993), Comp. Biochem. Physiol. B, 104, 567-575.
    View publication on PubMed
Search for more literature for 1.14.17.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.6
-
 ascorbate in the absence of Cu2+ Felis catus
1
-
 ascorbate in the presence of Cu2+ Felis catus
1.1
-
 ascorbate
-
 Rattus norvegicus
1.1
-
 ascorbate with or without Cu2+ Felis catus
2
-
 tyramine
-
 Felis catus
2.3
-
 tyramine
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+ enzyme not activated by exogenous copper but activity decreases at high concentrations Rattus norvegicus
Cu2+ enzyme not activated by exogenous copper but activity decreases at high concentrations Felis catus

Organism

Organism UniProt Comment Textmining
Felis catus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity in the cat is twofold higher compared to rat Rattus norvegicus
additional information
-
 activity in the cat is twofold higher compared to rat Felis catus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-dihydroxyphenethylamine + ascorbate + O2
-
 Rattus norvegicus noradrenaline + dehydroascorbate + H2O norepinephrine ?
tyramine + ascorbate + O2
-
 Rattus norvegicus octopamine + dehydroascorbate + H2O
-
 ?
tyramine + ascorbate + O2
-
 Felis catus octopamine + dehydroascorbate + H2O
-
 r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.6
-
-
 Rattus norvegicus
4.8 5
-
 Felis catus