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Literature summary for 1.14.16.5 extracted from
- Solubilization and partial characterization of alkylglycerol monooxygenase from rat liver microsomes (1983), Eur. J. Biochem., 132, 23-27.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| GSH | required for expression of full activity, maximal stimulation at 1 mM | Rattus norvegicus |  |
| Phospholipids | required for expression of full activity | Rattus norvegicus | |
| Triton X-100 | stimulates | Rattus norvegicus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| KCN | - |
Rattus norvegicus | |
| NEM | 8.0 mM | Rattus norvegicus | |
| PCMB | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.66 | - |
1-O-Hexadecylglycerol | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 400000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-O-hexadecylglycerol + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | 1-O-(1-hydroxy-hexadecyl)-sn-glycerol + dihydrobiopterin + H2O | - |
r | |
| hexadecylglycerol + tetrahydrobiopterin + O2 | 1-O-hexadecylglycerol | Rattus norvegicus | hexadecanal + glycerol + dihydrobiopterin + H2O | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 9.5 | pH 7.5: about 40% of maximal activity, pH 9.5: about 75% of maximal activity | Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| tetrahydrobiopterin | optimal concentration: 1 mM | Rattus norvegicus | |
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Release 2023.1 (January 2023)
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