Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-Dopa | noncompetitive vs. L-tryptophan and (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | Mus musculus | |
dopamine | noncompetitive vs. L-tryptophan and (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | Mus musculus | |
L-Dopa | noncompetitive vs. L-tryptophan and (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | Mus musculus | |
L-tyrosine | noncompetitive vs. L-tryptophan and (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00873 | - |
L-tryptophan | - |
Mus musculus | |
0.0344 | - |
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | biphasic kinetic, low Km value | Mus musculus | |
0.796 | - |
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | biphasic kinetic, high Km value | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
mastocytoma cell line P-815 | - |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.007 | - |
dopamine | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with high affinity | Mus musculus | |
0.0162 | - |
L-tyrosine | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with high affinity | Mus musculus | |
0.017 | - |
L-Dopa | vs. L-tryptophan | Mus musculus | |
0.0185 | - |
L-tyrosine | vs. L-tryptophan | Mus musculus | |
0.0393 | - |
dopamine | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with low affinity | Mus musculus | |
0.0761 | - |
D-Dopa | vs. L-tryptophan | Mus musculus | |
0.0803 | - |
L-Dopa | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with high affinity | Mus musculus | |
0.0887 | - |
L-Dopa | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with low affinity | Mus musculus | |
0.0943 | - |
dopamine | vs. L-tryptophan | Mus musculus | |
0.202 | - |
D-Dopa | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with low affinity | Mus musculus | |
0.306 | - |
L-tyrosine | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with low affinity | Mus musculus | |
0.609 | - |
D-Dopa | vs. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin, component with high affinity | Mus musculus |