Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Drosophila melanogaster | key enzyme in dopamine biosynthesis | ? | - |
? | |
additional information | Drosophila melanogaster | key enzyme in dopamine biosynthesis. Tissue-specific expression of the isoenzymes generated through alternative splicing of the tyrosine hydroxylase gene is a vital step in Drosophila development | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
central nervous system | isoenzyme DHT1 is selectively expressed in central nervous system. DTH1 cannot perform the function of the DTH II in the hypoderm | Drosophila melanogaster | - |
hypodermis | isoenzyme DHT2 is selectively expressed in central nervous system. DTH1 cannot perform the function of the DTH II in the hypoderm | Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + (6R)-5,6,7,8-tetrahydrobiopterin + O2 | - |
Drosophila melanogaster | 3,4-dihydroxyphenylalanine + ? | - |
? | |
additional information | key enzyme in dopamine biosynthesis | Drosophila melanogaster | ? | - |
? | |
additional information | key enzyme in dopamine biosynthesis. Tissue-specific expression of the isoenzymes generated through alternative splicing of the tyrosine hydroxylase gene is a vital step in Drosophila development | Drosophila melanogaster | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DTH1 | - |
Drosophila melanogaster |
DTH2 | - |
Drosophila melanogaster |
tyrosine hydroxylase | - |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
(6R)-5,6,7,8-tetrahydrobiopterin | - |
Drosophila melanogaster |