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Literature summary for 1.14.16.2 extracted from

  • Marles, L.K.; Peters, E.M.; Tobin, D.J.; Hibberts, N.A.; Schallreuter, K.U.
    Tyrosine hydroxylase isoenzyme I is present in human melanosomes: a possible novel function in pigmentation (2003), Exp. Dermatol., 12, 61-70.
    View publication on PubMed
Search for more literature for 1.14.16.2

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
melanosome
-
 Homo sapiens 42470
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens direct function for tyrosine hydroxylase in the melanosome via a cencerted action with tyrosinase to promote pigmentation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
keratinocyte undifferentiated, hydroxylase isoenzyme I mRNA, no detection of isoenzyme 2, 3 and 4 Homo sapiens
-
melanocyte epidermal, hydroxylase isoenzyme I mRNA, no detection of isoenzyme 2, 3 and 4 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0447
-
 activity in melanosomes Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information direct function for tyrosine hydroxylase in the melanosome via a cencerted action with tyrosinase to promote pigmentation Homo sapiens ?
-
 ?