Literature summary for 1.14.15.3 extracted from

Chang, Y.T.; Loew, G.H.
Homology modeling and substrate binding study of human CYP4A11 enzyme (1999), Proteins, 34, 403-415.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
arachidonic acid + NADPH + H+ + O2	Homo sapiens	-	20-hydroxyeicosatetraenoic acid + NADP+ + H2O	-	?
n-alkane + NAD(P)H + H+ + O2	Homo sapiens	-	n-alkanol + NAD(P)+ + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
arachidonic acid + NADPH + H+ + O2	-	Homo sapiens	20-hydroxyeicosatetraenoic acid + NADP+ + H2O	-	?
fatty acid + NAD(P)H + H+ + O2	3D-structure analysis, substrate pocket determination	Homo sapiens	omega-hydroxy fatty acid + NAD(P)+ + H2O	-	?
lauric acid + NAD(P)H + H+ + O2	-	Homo sapiens	12-hydroxydodecanoic acid + NAD(P)+ + H2O	-	?
n-alkane + NAD(P)H + H+ + O2	-	Homo sapiens	n-alkanol + NAD(P)+ + H2O	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Homo sapiens

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Release 2023.1 (January 2023)