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Literature summary for 1.14.14.32 extracted from

  • Neto, A.C.; Ball, B.A.; Browne, P.; Conley, A.J.
    Cellular localization of androgen synthesis in equine granulosa-theca cell tumors: Immunohistochemical expression of 17alpha-hydroxylase/17,20-lyase cytochrome P450 (2010), Theriogenology, 74, 393-401.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Equus sp.
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Source Tissue

Source Tissue Comment Organism Textmining
adrenal cortex
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Equus sp.
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interstitial cell is most consistent in the testicular interstitial cells surrounding existing or developing cysts Equus sp.
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Leydig cell
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Equus sp.
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additional information is localized primarily in theca interna of normal ovarian follicles, in theca-lutein cells of some corpora lutea, but not in granulosa-lutein cells. Is present in 14/30 GTCT cells (granulosa-theca cell tumors). Is absent from zona glomerulosa Equus sp.
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testis
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Equus sp.
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zona fasciculata
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Equus sp.
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Synonyms

Synonyms Comment Organism
17alpha-hydroxylase/17,20-lyase cytochrome P450
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Equus sp.
P450c17
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Equus sp.

General Information

General Information Comment Organism
physiological function enzyme is most directly responsible for androgen synthesis Equus sp.