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Literature summary for 1.14.14.32 extracted from

  • Kolar, N.W.; Swart, A.C.; Mason, J.I.; Swart, P.
    Functional expression and characterisation of human cytochrome P45017alpha in Pichia pastoris (2007), J. Biotechnol., 129, 635-644.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pichia pastoris Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
Homo sapiens androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Synonyms

Synonyms Comment Organism
C17,20 lyase
-
Homo sapiens
CYP17 catalyzes both steroid 17-hydroxylation and C17,20 lyase reactions Homo sapiens