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Literature summary for 1.14.14.32 extracted from

  • Nowotny, E.; Sananez, R.D.; Nattero, G.
    Bioconversion of steroids in vitro by testes from autoimmunized rabbits (1974), Hoppe-Seyler's Z. Physiol. Chem., 355, 716-720.
    View publication on PubMed
Search for more literature for 1.14.14.32

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Oryctolagus cuniculus enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes ?
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
 New Zealand rabbit
-

Reaction

Reaction Comment Organism Reaction ID
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2 = androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O bioconversion in vitro Oryctolagus cuniculus
a

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17alpha-hydroxyprogesterone + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryctolagus cuniculus androstenedione + acetate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information enzyme of the biosynthetic pathway for testosterone synthesis. Impairment of the reaction occurs in autoimmunized rabbits with severe damage of testes Oryctolagus cuniculus ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Oryctolagus cuniculus