Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.29 extracted from

  • Siam, A.; Brancale, A.; Simons, C.
    Comparative modeling of 25-hydroxycholesterol-7alpha-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations (2012), J. Mol. Model., 18, 441-453.
    View publication on PubMed
Search for more literature for 1.14.14.29

Inhibitors

Inhibitors Comment Organism Structure
3alpha-adiol
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
25-hydroxycholesterol + NADPH + H+ + O2 Homo sapiens
-
 ? + NADP+ + H2O
-
 ?
27-hydroxycholesterol + NADPH + H+ + O2 Homo sapiens
-
 3beta,7alpha-dihydroxy-5-cholestenoic acid + NADP+ + H2O
-
 ?
dehydroepiandrosterone + NADPH + H+ + o2 Homo sapiens
-
 7alpha-hydroxy-dehydroepiandrosterone + NADP+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O75881
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
25-hydroxycholesterol + NADPH + H+ + O2
-
 Homo sapiens ? + NADP+ + H2O
-
 ?
27-hydroxycholesterol + NADPH + H+ + O2
-
 Homo sapiens 3beta,7alpha-dihydroxy-5-cholestenoic acid + NADP+ + H2O
-
 ?
dehydroepiandrosterone + NADPH + H+ + o2
-
 Homo sapiens 7alpha-hydroxy-dehydroepiandrosterone + NADP+ + H2O
-
 ?

Synonyms

Synonyms Comment Organism
25-hydroxycholesterol-7alpha-hydroxylase
-
 Homo sapiens
CYP7B1
-
 Homo sapiens
oxysterol-7alpha-hydroxylase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Homo sapiens