Literature summary for 1.14.14.19 extracted from

Cui, Y.L.; Xue, Q.; Zheng, Q.C.; Zhang, J.L.; Kong, C.P.; Fan, J.R.; Zhang, H.X.
Structural features and dynamic investigations of the membrane-bound cytochrome P450 17A1 (2015), Biochim. Biophys. Acta, 1848, 2013-2021.

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Inhibitors

Inhibitors	Comment	Organism	Structure
abiraterone	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
a C21-steroid + [reduced NADPH-hemoprotein reductase] + O2	Homo sapiens	-	a 17alpha-hydroxy-C21-steroid + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P05093	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
a C21-steroid + [reduced NADPH-hemoprotein reductase] + O2	-	Homo sapiens	a 17alpha-hydroxy-C21-steroid + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Synonyms

Synonyms	Comment	Organism
CYP17A1	-	Homo sapiens
cytochrome P450 17A1	-	Homo sapiens
cytochrome P450c17	-	Homo sapiens

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Release 2023.1 (January 2023)