Inhibitors | Comment | Organism | Structure |
---|---|---|---|
20xi-hydroxy-21-trifluoropregn-4-en-3-one | at 0.0006 mM 50% inhibition | Rattus norvegicus | |
21-trifluoropregn-4-en-3,20-dione | at 0.0021 mM 50% inhibition | Rattus norvegicus | |
21-trifluoropregn-5-en-3beta,20xi-diol | at 0.0044 mM 50% inhibition | Rattus norvegicus | |
ketoconazole | at 0.0019 mM 50% inhibition | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pregnenolone + AH2 + O2 | Rattus norvegicus | - |
17alpha-hydroxypregnenolone + A + H2O | product eliminates at C20,21 acetate to yield dehydroepiandrosterone | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pregnenolone + AH2 + O2 | - |
Rattus norvegicus | 17alpha-hydroxypregnenolone + A + H2O | product eliminates at C20,21 acetate to yield dehydroepiandrosterone | ? |