Crystallization (Comment) | Organism |
---|---|
apo-enzyme and in complex with heme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isozyme HO-1 | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
protoheme + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 = biliverdin + Fe2+ + CO + 3 [oxidized NADPH-hemoprotein reductase] + 3 H2O | binding of heme stabilizes the solvent H-bonded network in the active site required for proper catalysis | Homo sapiens |